Archive for April 2015

Chokeberries may help cancer therapies

Chokeberries may have a role in helping cancer therapies- according to a study in the Journal of Clinical Pathology.

Chokeberries may have a role in helping cancer therapies- according to a study in the Journal of Clinical Pathology.Scientists suggest chokeberries could work in combination with conventional drugs to kill more cancer cells, but the UK research is at an early stage, with experiments carried out only on cancer cells in laboratories.

Researchers from the University of Southampton and King’s College Hospital London, tested a berry extract on pancreatic cancer samples.

Pancreatic cancer is particularly hard to treat and has an average survival period of just six months after diagnosis.

The study found that when the berry extract was used, together with a conventional chemotherapy drug called gemcitabine, more cancer cells died than when the drug was used alone.

But the scientists say the chokeberry had no effect on normal body cells tested in this way.

They believe compounds known as polyphenols in the chokeberries may reduce the number of harmful cells.

And the team previously carried out similar early work on brain cancer cells.

Henry Scowcroft, at the charity Cancer Research UK, said: “It’s far too early to say from this small laboratory study whether chemicals extracted from chokeberries have any effect on pancreatic cancer in patients.”

“And the findings certainly don’t suggest that the berries themselves should be taken alongside conventional chemotherapy. But innovative approaches are urgently needed to improve treatment for people with pancreatic cancer – a disease for which there has been precious little progress over recent decades.”

Chokeberries grow on the eastern side of North America in wetlands and swamp areas.

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Curry spice may boost and repair brains

A spice commonly found in curries may boost the brain’s ability to heal itself, according to a report in the journal Stem Cell Research and Therapy.

Curry spice may boost and repair brainsThe German study suggests a compound found in turmeric could encourage the growth of nerve cells thought to be part of the brain’s repair kit.

Scientists say this work- based in rats, may pave the way for future drugs for strokes and Alzheimer’s disease, but they say more trials are needed to see whether this applies to humans.

Researchers from the Institute of Neuroscience and Medicine in Julich, Germany, studied the effects of aromatic-turmerone – a compound found naturally in turmeric.

Rats were injected with the compound and their brains were then scanned.

Particular parts of the brain, known to be involved in nerve cell growth, were seen to be more active after the aromatic turmerone infusion.

Scientists say the compound may encourage a proliferation of brain cells.

In a separate part of the trial, researchers bathed rodent neural stem cells (NSCs) in different concentrations of aromatic tumerone extract.

NSCs have the ability to transform into any type of brain cell and scientists suggest they could have a role in repair after damage or disease.

Dr Maria Adele Rueger, who was part of the research team, said: “In humans and higher developed animals their abilities do not seem to be sufficient to repair the brain but in fish and smaller animals they seem to work well.”

The research found the higher the concentration of aromatic turmerone, the greater the growth of the NSCs.

And the cells bathed in the turmeric compound seemed to specialise into certain types of brain cells more rapidly too.

Dr Rueger added: “It is interesting that it might be possible to boost the effectiveness of the stem cells with aromatic-turmerone. And it is possible this in turn can help boost repair in the brain.”

She is now considering whether human trials may be feasible.

Aromatic turmerone is the lesser studied of two major compounds in turmeric that may have an effect on the human body.

Previous studies suggest the other compound, curcumin, could reduce inflammation in the body and have anti cancer benefits.

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